Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19154331 | 0.88 | OPRM1 (0.73) | OPRM1OPRL1 | |
| SCHEMBL19096494 | 0.86 | OPRM1 (1.00) | OPRM1OPRL1 | |
| SCHEMBL19096492 | 0.86 | OPRM1 (1.00) | OPRM1OPRL1 | |
| SCHEMBL19107182 | 0.86 | OPRM1 (1.00) | OPRM1OPRL1 | |
| SCHEMBL22269269 | 0.86 | OPRM1 (0.73) | OPRM1OPRL1 | |
| SCHEMBL19154316 | 0.79 | OPRM1 (0.63) | OPRM1OPRL1 | |
| SCHEMBL23514232 | 0.78 | OPRM1 (1.00) | OPRM1OPRL1 | |
| SCHEMBL19096447 | 0.78 | OPRM1 (1.00) | OPRM1OPRL1 | |
| SCHEMBL19107231 | 0.78 | OPRM1 (1.00) | OPRM1OPRL1 | |
| SCHEMBL19096448 | 0.78 | OPRM1 (1.00) | OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017121648-A1 | 3-((HETERO-)ARYL)-ALKYL-8-AMINO-2-OXO-1,3-DIAZA-SPIRO-[4.5]-DECANE DERIVATIVES | Grünenthal GmbH (DE) | 2017-07-20 | — | — | WO | disclosed |