Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 19/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 19/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21766347 | 0.87 | OPRM1 (0.48) | OPRL1OPRM1 | |
| SCHEMBL21766365 | 0.86 | OPRL1 (0.46) | OPRL1OPRM1 | |
| SCHEMBL22560734 | 0.83 | OPRL1 (0.50) | OPRL1OPRM1 | |
| SCHEMBL19145436 | 0.81 | OPRL1 (0.54) | OPRL1OPRM1 | |
| SCHEMBL25680098 | 0.81 | OPRL1 (0.44) | OPRL1OPRM1 | |
| SCHEMBL21766368 | 0.80 | OPRL1 (0.54) | OPRL1OPRM1 | |
| SCHEMBL4702248 | 0.79 | OPRL1 (0.55) | OPRL1OPRM1 | |
| SCHEMBL21766362 | 0.78 | OPRL1 (0.56) | OPRL1OPRM1 | |
| SCHEMBL21766632 | 0.76 | OPRL1 (0.56) | OPRL1OPRM1 | |
| SCHEMBL20866634 | 0.75 | OPRM1 (0.43) | OPRL1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017121649-A1 | 3-(CARBOXYMETHYL)-8-AMINO-2-OXO-1,3-DIAZA-SPIRO-[4.5]-DECANE DERIVATIVES | Grünenthal GmbH (DE) | 2017-07-20 | — | — | WO | disclosed |