Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 19/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 17/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21766368 | 0.90 | OPRL1 (0.54) | OPRL1OPRM1OPRK1 | |
| SCHEMBL19145436 | 0.89 | OPRL1 (0.54) | OPRL1OPRM1OPRK1 | |
| SCHEMBL21766632 | 0.88 | OPRL1 (0.56) | OPRL1OPRM1 | |
| SCHEMBL25678122 | 0.87 | OPRL1 (0.60) | OPRL1OPRM1OPRK1 | |
| SCHEMBL2780075 | 0.84 | ALDH1A1 (0.53) | OPRL1OPRM1OPRK1 | |
| SCHEMBL19148275 | 0.82 | OPRL1 (0.48) | OPRL1OPRM1OPRK1 | |
| SCHEMBL19146068 | 0.82 | OPRL1 (0.58) | OPRL1OPRM1OPRK1 | |
| SCHEMBL2780290 | 0.81 | OPRL1 (0.59) | OPRL1OPRM1OPRK1 | |
| SCHEMBL4849182 | 0.81 | OPRM1 (0.74) | OPRL1OPRM1 | |
| Hydrochloric Acid SCHEMBL4852374 | 0.80 | OPRM1 (0.75) | OPRL1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560823-B1 | 4-SUBSTITUTED 1-AMINOCYCLOHEXANE DERIVATIVES FOR UTILIZATION AS ORL1-RECEPTOR AND MU-OPIATE RECEPTOR LIGANDS | GRUENENTHAL GMBH (DE) | 2008-07-09 | — | — | EP | disclosed |
| EP-1560823-A1 | 4-SUBSTITUTED 1-AMINOCYCLOHEXANE DERIVATIVES FOR UTILIZATION AS ORL1-RECEPTOR AND MU-OPIATE RECEPTOR LIGANDS | Grünenthal GmbH (DE) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004043949-A1 | 4-SUBSTITUTED 1-AMINOCYCLOHEXANE DERIVATIVES FOR UTILIZATION AS ORL1-RECEPTOR AND MU-OPIATE RECEPTOR LIGANDS | Grünenthal GmbH (DE) | 2004-05-27 | — | — | WO | disclosed |