SCHEMBL19152161

SCHEMBL19152161

N=c1ccncn1C(N)=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.36
SIRT3 Q9NTG7 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
KDM4E B2RXH2 1/20 0.31
MPO P05164 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2A6 P11509 1/20 0.31
CYP2C19 P33261 1/20 0.31
NAPRT Q6XQN6 1/20 0.31
CCNC P24863 1/20 0.31
CDK8 P49336 1/20 0.31
CA1 P00915 1/20 0.31
CA9 Q16790 1/20 0.31
TSHR P16473 1/20 0.31
GAA P10253 1/20 0.31
F7 P08709 1/20 0.31
F3 P13726 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7096286 0.78 ALDH1A1 (0.38) PARP1SIRT3TDP1KDM4EMPO
SCHEMBL19152160 0.68 PARP1 (0.36) PARP1SIRT3TDP1ADORA3TSHR
SCHEMBL3173808 0.67 INMT (0.40) PARP1TDP1KDM4ECYP3A4CYP2C19
SCHEMBL24249640 0.65 ALDH1A1 (0.35) PARP1KDM4ECYP1A2
SCHEMBL18663431 0.64 MEN1 (0.35) PARP1KDM4ECA1
SCHEMBL3134031 0.64
SCHEMBL5030414 0.63 FGFR1 (0.46) PARP1SIRT3TDP1KDM4EADORA3
SCHEMBL16197154 0.63 SIRT3 (0.36) PARP1SIRT3TDP1KDM4EADORA3
SCHEMBL11007100 0.63
SCHEMBL28059053 0.63 ALDH1A1 (0.42) TDP1KDM4ECYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3402797-B1 HETEROCYCLE DERIVATIVES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2020-02-19 EP disclosed
WO-2017121674-A1 HETEROCYCLENE DERIVATIVES AS PEST CONTROL AGENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-07-20 WO disclosed