Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18238020 | 0.77 | ALDH1A1 (0.41) | ALDH1A1HSD17B10KDM4EHPGDMAPK1 | |
| SCHEMBL18238019 | 0.77 | ALDH1A1 (0.39) | ALDH1A1HSD17B10KDM4EHPGDMAPK1 | |
| SCHEMBL19152813 | 0.73 | ALDH1A1 (0.47) | ALDH1A1HSD17B10KDM4EHPGDMAPK1 | |
| SCHEMBL19153314 | 0.72 | ALDH1A1 (0.46) | ALDH1A1HSD17B10KDM4EHPGDMAPK1 | |
| SCHEMBL19153373 | 0.72 | ALDH1A1 (0.46) | ALDH1A1HSD17B10KDM4EPARP1PRKCI | |
| SCHEMBL19153956 | 0.70 | ALDH1A1 (0.44) | ALDH1A1HSD17B10KDM4EHPGDMAPK1 | |
| SCHEMBL16007970 | 0.68 | ALDH1A1 (0.50) | ALDH1A1HSD17B10KDM4EHPGDMAPK1 | |
| SCHEMBL24757251 | 0.67 | ALDH1A1 (0.44) | ALDH1A1HSD17B10KDM4EHPGDMAPK1 | |
| SCHEMBL1009329 | 0.67 | HSD17B10 (0.52) | ALDH1A1HSD17B10KDM4EHPGDMAPK1 | |
| SCHEMBL13659509 | 0.67 | ALDH1A1 (0.53) | ALDH1A1HSD17B10KDM4EHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170202970-A1 | SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME | BLINKBIO, INC. | 2017-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170202970-A1 | SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME | CD44, MSN, AS3MT | ALDH1A1 2151/4885HSD17B10 3435/4885KDM4E 3060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.