Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19153920 | 0.93 | PDPK1 (0.31) | PDPK1 | |
| SCHEMBL18238800 | 0.79 | PARP1 (0.34) | PARP1 | |
| SCHEMBL17232740 | 0.79 | ALDH1A1 (0.30) | — | |
| SCHEMBL19153230 | 0.79 | CYP2C19 (0.33) | — | |
| SCHEMBL19131108 | 0.76 | PARP1 (0.34) | PARP1 | |
| SCHEMBL22743476 | 0.74 | PARP1 (0.45) | PARP1 | |
| SCHEMBL19902649 | 0.74 | PARP1 (0.42) | PARP1 | |
| SCHEMBL19152700 | 0.72 | PDPK1 (0.31) | PDPK1 | |
| SCHEMBL19152698 | 0.71 | PDPK1 (0.30) | PDPK1 | |
| SCHEMBL19152701 | 0.71 | DYRK1A (0.32) | PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170202970-A1 | SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME | BLINKBIO, INC. | 2017-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170202970-A1 | SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME | CD44, MSN, AS3MT | PARP1 2195/4885PDPK1 2826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.