Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.34 |
| ▸ | ABAT | P80404 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1915657 | 0.95 | KMT2A (0.41) | KMT2AALDH1A1ESR1CYP3A4ESR2 | |
| SCHEMBL1916098 | 0.94 | KMT2A (0.41) | KMT2AALDH1A1ESR1CYP3A4ESR2 | |
| SCHEMBL1916607 | 0.90 | ALDH1A1 (0.41) | KMT2AALDH1A1ESR1CYP3A4ESR2 | |
| SCHEMBL4221554 | 0.81 | ESR1 (0.54) | ALDH1A1ESR1CYP3A4ESR2RAB9A | |
| SCHEMBL523363 | 0.81 | HDAC3 (0.47) | ALDH1A1MAPK1SMN1; SMN2HDAC3ADRA1A | |
| SCHEMBL4025460 | 0.80 | CHEK1 (0.39) | KMT2AALDH1A1ESR1CYP3A4ESR2 | |
| SCHEMBL1915421 | 0.80 | ALDH1A1 (0.44) | KMT2AALDH1A1EPHX2NR1H4ALDH5A1 | |
| SCHEMBL1915298 | 0.77 | KMT2A (0.39) | KMT2AALDH1A1EPHX2NR1H4ALDH5A1 | |
| SCHEMBL20564637 | 0.76 | HDAC3 (0.47) | ALDH1A1PPARAMAPK1SMN1; SMN2HDAC3 | |
| SCHEMBL4214690 | 0.75 | ESR1 (0.51) | ALDH1A1ESR1CYP3A4ESR2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130018140-A1 | N-BRIDGED POLYNITRONS AND THE USE THEREOF AS CROSS-LINKING AGENTS, IN PARTICULAR IN COATING MATERIALS AND ADHESIVES | DICKMEIS MARCUS (DE) | 2013-01-17 | — | — | US | disclosed |
| EP-2516532-A2 | POLYOXAZIRIDINES AND USE THEREOF AS A CROSS-LINKING AGENT, ESPECIALLY IN COATING MATERIALS AND ADHESIVES | Dickmeis, Marcus (DE) | 2012-10-31 | — | — | EP | disclosed |
| EP-2516531-A1 | N-BRIDGED POLYNITRONS AND THE USE THEREOF AS CROSS-LINKERS, IN PARTICULAR IN COATING MATERIALS AND ADHESIVES | Dickmeis, Marcus (DE) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011085793-A2 | POLYOXAZIRIDINES AND USE THEREOF AS A CROSS-LINKING AGENT, ESPECIALLY IN COATING MATERIALS AND ADHESIVES | DICKMEIS MARCUS (DE) | 2011-07-21 | — | — | WO | disclosed |
| WO-2011076392-A1 | N-BRIDGED POLYNITRONS AND THE USE THEREOF AS CROSS-LINKERS, IN PARTICULAR IN COATING MATERIALS AND ADHESIVES | DICKMEIS MARCUS (DE) | 2011-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130018140-A1 | N-BRIDGED POLYNITRONS AND THE USE THEREOF AS CROSS-LINKING AGENTS, IN PARTICULAR IN COATING MATERIALS AND ADHESIVES | PNN, PARN, NCLN | KMT2A 631/4885ALDH1A1 1538/4885ESR1 4049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.