Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19153767 | 0.85 | PDPK1 (0.36) | PDPK1CRBNDYRK1A | |
| SCHEMBL18238937 | 0.77 | PARP1 (0.33) | CRBNPARP1 | |
| SCHEMBL19153335 | 0.77 | CRBN (0.39) | PDPK1CRBN | |
| SCHEMBL19153334 | 0.73 | CRBN (0.39) | PDPK1CRBN | |
| SCHEMBL18238938 | 0.70 | CRBN (0.32) | CRBNPARP1 | |
| SCHEMBL19152698 | 0.70 | PDPK1 (0.30) | PDPK1 | |
| SCHEMBL19902649 | 0.68 | PARP1 (0.42) | PARP1 | |
| SCHEMBL22743476 | 0.68 | PARP1 (0.45) | PARP1 | |
| SCHEMBL11963499 | 0.65 | CRBN (0.39) | CRBN | |
| SCHEMBL22743450 | 0.64 | PDPK1 (0.31) | PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170202970-A1 | SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME | BLINKBIO, INC. | 2017-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170202970-A1 | SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME | CD44, MSN, AS3MT | PDPK1 2826/4885CRBN 1246/4885DYRK1A 1107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.