SCHEMBL19155181

SCHEMBL19155181

c1ccc2cc(Cc3ccc4c(c3)oc3ccccc34)ccc2c1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 2/20 0.56
AHR P35869 2/20 0.47
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
MAPT P10636 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
HPGD P15428 1/20 0.46
CTRC Q99895 1/20 0.43
PTPN1 P18031 1/20 0.43
CYP1A2 P05177 2/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C19 P33261 1/20 0.43
CYP2A6 P11509 1/20 0.43
DUSP3 P51452 1/20 0.42
PDE10A Q9Y233 3/20 0.41
ALOX5 P09917 1/20 0.41
MME P08473 1/20 0.40
ECE1 P42892 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24634423 0.90 NQO1 (0.56) NQO1AHRMEN1KMT2AMAPT
SCHEMBL19155292 0.84 AHR (0.52) NQO1AHRMEN1KMT2AMAPT
SCHEMBL24400973 0.78 CYP1A2 (0.46) NQO1AHRMEN1KMT2AMAPT
SCHEMBL2838141 0.78 CYP1A2 (0.65) KMT2ACTRCCYP1A2CYP2D6CYP2A6
SCHEMBL4149801 0.77 HCRTR1 (0.52) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL19768725 0.77 CYP1A2 (0.57) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL24787837 0.76 MAOB (0.50) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL24677494 0.76 CYP1A2 (0.50) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL22879786 0.76 ECE1 (0.47) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL23098893 0.76 GPR55 (0.47) KMT2AMAPTKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9716233-B2 Electronic device including a fluoranthene derivative E I DU PONT DE NEMOURS AND COMPANY (US) 2017-07-25 US disclosed