SCHEMBL1915564

SCHEMBL1915564

O=C(O)C[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CPA1 P15085 9/20 1.00
CPA3 P15088 3/20 1.00
CPB1 P15086 1/20 1.00
CPB2 Q96IY4 1/20 1.00
CYP1A2 P05177 1/20 0.76
FOLH1 Q04609 2/20 0.67
MME P08473 1/20 0.66
LTA4H P09960 2/20 0.63
SLC1A3 P43003 1/20 0.59
SLC1A2 P43004 1/20 0.59
SLC1A1 P43005 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL393002 1.00 CPA1 (1.00) CPA1CPA3CPB1CPB2CYP1A2
SCHEMBL5688996 1.00 CPA1 (1.00) CPA1CPA3CPB1CPB2CYP1A2
SCHEMBL3421012 0.98 CPA1 (0.96) CPA1CPA3CPB1CPB2CYP1A2
Succinic Acid SCHEMBL28290802 0.94 CPA1 (0.89) CPA1CPA3CPB1CPB2CYP1A2
Alcohol SCHEMBL28211096 0.93 CPA1 (0.86) CPA1CPA3CPB1CPB2CYP1A2
SCHEMBL17537907 0.91 CPA1 (0.84) CPA1CPA3CPB1CPB2CYP1A2
SCHEMBL4664822 0.87 CYP1A2 (1.00) CPA1CPA3CPB1CPB2CYP1A2
N-Benzylmethylamine SCHEMBL27642828 0.87 CPA1 (0.75) CPA1CPA3CPB1CPB2CYP1A2
SCHEMBL20560513 0.86 CPA1 (0.74) CPA1CPA3CPB1CPB2CYP1A2
SCHEMBL27642829 0.85 CPA1 (0.73) CPA1CPA3CPB1CPB2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112557566-A Method for detecting corresponding isomer of mitiglinide calcium intermediate S-benzylsuccinic acid 江西济民可信药业有限公司 2021-03-26 CN claimed
CN-111253244-B Recycling method of (S) -2-benzylsuccinic acid resolution mother liquor 山东铂源药业有限公司 2020-10-16 CN claimed
CN-111253244-A Recycling method of (S) -2-benzylsuccinic acid resolution mother liquor 山东铂源药业有限公司 2020-06-09 CN claimed
CN-110256328-A A kind of preparation method of R- Mitiglinide Calcium 江西济民可信药业有限公司 2019-09-20 CN claimed
CN-105418401-B The preparation method of one kind (S) -2- benzyl succinic acid 威海迪素制药有限公司 2019-03-05 CN claimed
EP-0512415-B1 Process for the enantioselective synthesis of 2(R)-benzyl succanamide derivatives HOECHST AG (DE) 1997-08-06 EP claimed
US-5321139-A Amination of phenylitaconic anhydride, catalytic reduction of formed amide; renin inhibitor HOECHST AKTIENGESELLSCHAFT (DE) 1994-06-14 US claimed
JP-5170718-A None JP disclosed
JP-10237013-A None JP disclosed
JP-10212262-A None JP disclosed
JP-10248592-A None JP disclosed
US-20250313871-A1 BIOCHEMICAL PATHWAY FOR THE PRODUCTION OF TULIPALIN A VIA ITACONIC ACID MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) 2025-10-09 US disclosed
US-20240309417-A1 Bioconversion of Short-Chain Hydrocarbons to Fuels and Chemicals GONZALEZ RAMON (US) 2024-09-19 US disclosed
US-5063208-A Cardiovascular disorders, vision defects ABBOTT LABORATORIES (US) 1991-11-05 US disclosed
EP-0438233-A2 Orally active renin inhibitors PFIZER INC. (US) 1991-07-24 EP disclosed
EP-0427939-A2 Renin inhibitors AMERICAN CYANAMID COMPANY (US) 1991-05-22 EP disclosed
WO-1991005763-A1 DIPEPTIDE-ANALOG-BASED METALLOENDOPEPTIDASE INHIBITORS AND METHODS OF USING SAME THE SALK INSTITUTE BIOTECHNOLOGY/INDUSTRIAL ASSOCIATES, INC. (US) 1991-05-02 WO disclosed
EP-0410260-A2 Peptidyl aminodiol renin inhibitors ABBOTT LABORATORIES (US) 1991-01-30 EP disclosed
EP-0380463-A2 Method for preparing (R)-succinic acid derivatives MONSANTO COMPANY (US) 1990-08-01 EP disclosed
US-4939288-A Catalytic hydrogenation MONSANTO COMPANY (US) 1990-07-03 US disclosed