SCHEMBL3421012

SCHEMBL3421012

O=C(O)CC(Cc1ccccc1)C(=O)O.[CsH]

nearest known ligand 0.96

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ CPA1 P15085 9/20 0.96
▸ CPA3 P15088 3/20 0.96
▸ CPB1 P15086 1/20 0.96
▸ CPB2 Q96IY4 1/20 0.96
▸ CYP1A2 P05177 1/20 0.73
▸ FOLH1 Q04609 2/20 0.65
▸ MME P08473 1/20 0.64
▸ LTA4H P09960 2/20 0.61
▸ SLC1A3 P43003 1/20 0.58
▸ SLC1A2 P43004 1/20 0.58
▸ SLC1A1 P43005 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL393002 0.98 CPA1 (1.00) CPA1CPA3CPB1CPB2CYP1A2
SCHEMBL1915564 0.98 CPA1 (1.00) CPA1CPA3CPB1CPB2CYP1A2
SCHEMBL5688996 0.98 CPA1 (1.00) CPA1CPA3CPB1CPB2CYP1A2
Succinic Acid SCHEMBL28290802 0.92 CPA1 (0.89) CPA1CPA3CPB1CPB2CYP1A2
Alcohol SCHEMBL28211096 0.91 CPA1 (0.86) CPA1CPA3CPB1CPB2CYP1A2
SCHEMBL17537907 0.90 CPA1 (0.84) CPA1CPA3CPB1CPB2CYP1A2
SCHEMBL4664822 0.85 CYP1A2 (1.00) CPA1CPA3CPB1CPB2CYP1A2
N-Benzylmethylamine SCHEMBL27642828 0.85 CPA1 (0.75) CPA1CPA3CPB1CPB2CYP1A2
SCHEMBL20560513 0.84 CPA1 (0.74) CPA1CPA3CPB1CPB2CYP1A2
SCHEMBL27642829 0.84 CPA1 (0.73) CPA1CPA3CPB1CPB2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1687609-B1 FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND EPOCH BIOSCIENCES INC (US) 2014-12-10 — — EP disclosed
US-7759126-B2 Real-time linear detection probes: sensitive 5′-minor groove binder-containing probes for amplification (or PCR) analysis ELITECH HOLDING B.V. (NL) 2010-07-20 — — US disclosed
US-20080293586-A1 FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND EPOCH BIOSCIENCES, INC. (US) 2008-11-27 — — US disclosed
US-7381818-B2 Fluorescent probes containing 5′-minor groove binder, fluorophore and quenching moieties and methods of use thereof EPOCH BIOSCIENCES, INC. (US) 2008-06-03 — — US disclosed
EP-1687609-A2 FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND Epoch Biosciences, Inc. (US) 2006-08-09 — — EP disclosed
US-20050214797-A1 Fluorescent probes for DNA detection by hybridization with improved sensitivity and low background EPOCH BIOSCIENCES, INC (US) 2005-09-29 — — US disclosed
WO-2005043127-A2 FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND EPOCH BIOSCIENCES, INC. (US) 2005-05-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080293586-A1 FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND SSBP1, DDB1, DNA2 CPA1 4218/4885CPA3 4642/4885CPB1 755/4885
US-20050214797-A1 Fluorescent probes for DNA detection by hybridization with improved sensitivity and low background SSBP1, DDB1, DNA2 CPA1 4218/4885CPA3 4642/4885CPB1 755/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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