Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 5/20 | 0.89 |
| ▸ | CPA3 | P15088 | 3/20 | 0.89 |
| ▸ | CPB1 | P15086 | 1/20 | 0.89 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.89 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.61 |
| ▸ | MME | P08473 | 1/20 | 0.60 |
| ▸ | LTA4H | P09960 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1915564 | 0.94 | CPA1 (1.00) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL5688996 | 0.94 | CPA1 (1.00) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL393002 | 0.94 | CPA1 (1.00) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL3421012 | 0.92 | CPA1 (0.96) | CPA1CPA3CPB1CPB2CYP1A2 | |
| Alcohol SCHEMBL28211096 | 0.87 | CPA1 (0.86) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL17537907 | 0.86 | CPA1 (0.84) | CPA1CPA3CPB1CPB2CYP1A2 | |
| Dodecanoate SCHEMBL8723704 | 0.85 | CPA1 (0.69) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL3963424 | 0.83 | CPA3 (1.00) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL29088272 | 0.83 | CPA3 (1.00) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL4664822 | 0.82 | CYP1A2 (1.00) | CPA1CPA3CPB1CPB2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109580821-A | The detection method of impurity succinic acid in a kind of S- benzyl succinic acid | 山东铂源药业有限公司 | 2019-04-05 | — | — | CN | disclosed |