Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 4/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21902128 | 0.80 | ALDH1A1 (0.37) | ALDH1A1CA1ESR1P2RX7LMNA | |
| SCHEMBL16853373 | 0.74 | MEN1 (0.40) | — | |
| SCHEMBL2633665 | 0.74 | ALDH1A1 (0.44) | ALDH1A1CA1P2RX7LMNAPKM | |
| SCHEMBL13334898 | 0.73 | — | — | |
| SCHEMBL16853203 | 0.73 | SMYD3 (0.34) | — | |
| SCHEMBL25129079 | 0.72 | ALDH1A1 (0.39) | ALDH1A1CA1P2RX7LMNAPKM | |
| SCHEMBL19062210 | 0.72 | ALDH1A1 (0.39) | ALDH1A1CA1ESR1P2RX7LMNA | |
| SCHEMBL13334643 | 0.72 | MEN1 (0.32) | — | |
| SCHEMBL25129044 | 0.71 | ALDH1A1 (0.38) | ALDH1A1CA1P2RX7LMNAPKM | |
| SCHEMBL13334844 | 0.71 | PAOX (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9714421-B2 | Compositions and methods | IONIS PHARMACEUTICALS, INC. (US) | 2017-07-25 | — | — | US | disclosed |