Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16853203 | 0.82 | SMYD3 (0.34) | MMP8SMN1; SMN2HSD17B10CYP2D6CYP2C19 | |
| SCHEMBL16383649 | 0.80 | MEN1 (0.34) | MEN1KMT2APSMB5CYP2C9MTNR1A | |
| SCHEMBL19561380 | 0.79 | CYP2D6 (0.48) | MMP8SMN1; SMN2HSD17B10CYP2D6CYP2C19 | |
| SCHEMBL12847744 | 0.79 | MEN1 (0.46) | MEN1KMT2APSMB5SMN1; SMN2HSD17B10 | |
| SCHEMBL13773142 | 0.78 | MMP8 (0.33) | KMT2AMMP8SMN1; SMN2HSD17B10CYP2C9 | |
| SCHEMBL619040 | 0.77 | MEN1 (0.44) | MEN1KMT2ASMN1; SMN2HSD17B10CYP2C9 | |
| SCHEMBL18923056 | 0.75 | MEN1 (0.43) | MEN1KMT2APSMB5SMN1; SMN2CYP2C9 | |
| SCHEMBL18569933 | 0.75 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2HSD17B10CYP2C9 | |
| SCHEMBL21793207 | 0.74 | ALDH1A1 (0.36) | MEN1KMT2APSMB5MMP8SMN1; SMN2 | |
| SCHEMBL19155877 | 0.74 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4212180-A1 | MODIFIED THERAPEUTIC AGENTS, STAPLED PEPTIDE LIPID CONJUGATES, AND COMPOSITIONS THEREOF | The Scripps Research Institute (US) | 2023-07-19 | — | — | EP | disclosed |
| WO-2022253283-A1 | PROTEIN KINASE DEGRADANT AND USE THEREOF | 中国科学院上海有机化学研究所 | 2022-12-08 | — | — | WO | disclosed |
| WO-2015095406-A1 | MODIFIED THERAPEUTIC AGENTS, STAPLED PEPTIDE LIPID CONJUGATES, AND COMPOSITIONS THEREOF | THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2015-06-25 | — | — | WO | disclosed |