Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20083950 | 0.87 | KDR (0.46) | KDRKDM1AMAOBMEN1KMT2A | |
| SCHEMBL20083999 | 0.81 | KDR (0.43) | KDRKDM1AMEN1KMT2ALMNA | |
| SCHEMBL15276969 | 0.76 | LMNA (0.50) | KDRMEN1KMT2ALMNATSHR | |
| SCHEMBL21844850 | 0.74 | KDR (0.43) | KDRMEN1KMT2ALMNAROCK2 | |
| SCHEMBL15276968 | 0.71 | LMNA (0.52) | KDRMEN1KMT2ALMNATSHR | |
| SCHEMBL21844897 | 0.71 | NPC1 (0.51) | KDM1AMAOBMEN1KMT2ALMNA | |
| SCHEMBL19157292 | 0.67 | KCNK3 (0.69) | MEN1KMT2A | |
| SCHEMBL15276967 | 0.66 | LMNA (0.47) | KDRMEN1KMT2ALMNATSHR | |
| SCHEMBL15076311 | 0.65 | LMNA (0.47) | MEN1KMT2ALMNATSHR | |
| SCHEMBL15076310 | 0.65 | MEN1 (0.52) | MEN1KMT2ALMNATSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794565-B1 | HEPATITIS B ANTIVIRAL AGENTS | NOVIRA THERAPEUTICS INC (US) | 2017-07-26 | — | — | EP | disclosed |