SCHEMBL1915741

SCHEMBL1915741

CCCCCC(Oc1ccc(C=O)cc1)Oc1ccc(C=O)cc1

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A3 P47895 2/20 0.53
ALDH1A1 P00352 4/20 0.45
LMNA P02545 1/20 0.45
MAPT P10636 1/20 0.45
HPGD P15428 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
DRD1 P21728 1/20 0.45
CYP2A6 P11509 2/20 0.44
KMT2A Q03164 1/20 0.40
ALDH3A1 P30838 1/20 0.38
TYR P14679 1/20 0.36
STS P08842 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C19 P33261 1/20 0.36
SLC2A1 P11166 1/20 0.36
SMPD1 P17405 3/20 0.35
PPARG P37231 1/20 0.34
PPARA Q07869 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14003721 0.98 ALDH1A3 (0.51) ALDH1A3ALDH1A1LMNAMAPTHPGD
SCHEMBL1915454 0.98 ALDH1A3 (0.51) ALDH1A3ALDH1A1LMNAMAPTHPGD
SCHEMBL8192949 0.95 ALDH1A3 (0.55) ALDH1A3ALDH1A1LMNAMAPTHPGD
SCHEMBL1915714 0.88 ALDH1A3 (0.58) ALDH1A3ALDH1A1LMNAMAPTHPGD
SCHEMBL29283465 0.85 ALDH1A3 (0.51) ALDH1A3ALDH1A1LMNAMAPTHPGD
SCHEMBL10624640 0.84 ALDH1A3 (0.54) ALDH1A3ALDH1A1LMNAMAPTHPGD
SCHEMBL6142512 0.84 ALDH1A3 (0.50) ALDH1A3ALDH1A1LMNAMAPTHPGD
SCHEMBL11442565 0.84 ALDH1A3 (0.54) ALDH1A3ALDH1A1LMNAMAPTHPGD
SCHEMBL12318699 0.84 ALDH1A3 (0.50) ALDH1A3ALDH1A1LMNAMAPTHPGD
SCHEMBL13821491 0.84 THRB (0.45) ALDH1A3ALDH1A1LMNAMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2516531-A1 N-BRIDGED POLYNITRONS AND THE USE THEREOF AS CROSS-LINKERS, IN PARTICULAR IN COATING MATERIALS AND ADHESIVES Dickmeis, Marcus (DE) 2012-10-31 EP disclosed
EP-2516532-A2 POLYOXAZIRIDINES AND USE THEREOF AS A CROSS-LINKING AGENT, ESPECIALLY IN COATING MATERIALS AND ADHESIVES Dickmeis, Marcus (DE) 2012-10-31 EP disclosed
WO-2011085793-A2 POLYOXAZIRIDINES AND USE THEREOF AS A CROSS-LINKING AGENT, ESPECIALLY IN COATING MATERIALS AND ADHESIVES DICKMEIS MARCUS (DE) 2011-07-21 WO disclosed
WO-2011076392-A1 N-BRIDGED POLYNITRONS AND THE USE THEREOF AS CROSS-LINKERS, IN PARTICULAR IN COATING MATERIALS AND ADHESIVES DICKMEIS MARCUS (DE) 2011-06-30 WO disclosed