Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 9/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27255246 | 1.00 | POLB (0.42) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL19624380 | 0.93 | POLB (0.43) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL19914776 | 0.93 | POLB (0.43) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL16559853 | 0.92 | POLB (0.48) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL16351987 | 0.92 | POLB (0.48) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL16559844 | 0.91 | POLB (0.47) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL16559827 | 0.91 | POLB (0.47) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL25795454 | 0.89 | POLB (0.36) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL19187256 | 0.88 | POLB (0.52) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL18500413 | 0.87 | POLB (0.44) | POLBAPEX1HTTTDP1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2818531-B1 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2017-07-26 | — | — | EP | disclosed |