Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | RARB | P10826 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4447276 | 0.90 | POLB (0.61) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL24684595 | 0.89 | POLB (0.50) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL27255246 | 0.88 | POLB (0.42) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL19157428 | 0.88 | POLB (0.42) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL21889394 | 0.87 | POLB (0.58) | POLBAPEX1HTTTDP1RARB | |
| SCHEMBL454606 | 0.85 | POLB (0.67) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL19624380 | 0.85 | POLB (0.43) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL19914776 | 0.85 | POLB (0.43) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL18308843 | 0.84 | POLB (0.56) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL1494215 | 0.84 | POLB (0.56) | POLBAPEX1HTTTDP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3199558-A1 | COMPOUND HAVING FOUR POLYMERIZABLE GROUPS, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC Corporation (JP) | 2017-08-02 | — | — | EP | disclosed |