Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.67 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.59 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.59 |
| ▸ | PNP | P00491 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.56 |
| ▸ | PDE2A | O00408 | 3/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | NT5E | P21589 | 2/20 | 0.51 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19157586 | 0.87 | ADORA3 (0.50) | ADORA3PDE4DPDE3APNPLMNA | |
| SCHEMBL3436977 | 0.84 | PDE4D (0.66) | ADORA3PDE4DPDE3APNPLMNA | |
| SCHEMBL3436979 | 0.84 | PDE4D (0.66) | ADORA3PDE4DPDE3APNPLMNA | |
| SCHEMBL19959557 | 0.84 | PDE4D (0.66) | ADORA3PDE4DPDE3APNPLMNA | |
| SCHEMBL21088897 | 0.82 | PDE4D (0.73) | ADORA3PDE4DPDE3APNPLMNA | |
| SCHEMBL21089006 | 0.82 | PDE4D (0.73) | ADORA3PDE4DPDE3APNPLMNA | |
| SCHEMBL10015808 | 0.82 | PDE4D (0.73) | ADORA3PDE4DPDE3APNPLMNA | |
| SCHEMBL14304622 | 0.81 | AHCY (0.58) | ADORA3SMN1; SMN2ADORA2AADORA1ADORA2B | |
| SCHEMBL19843960 | 0.81 | ADORA3 (1.00) | ADORA3PDE4DPDE3ALMNATP53 | |
| SCHEMBL3877328 | 0.81 | ADORA3 (1.00) | ADORA3PDE4DPDE3ALMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3134537-B1 | METHOD FOR THE SYNTHESIS OF CLOFARABINE | SYNBIAS PHARMA AG (CH) | 2017-07-26 | — | — | EP | disclosed |