Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 13/20 | 0.39 |
| ▸ | LATS2 | Q9NRM7 | 9/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | PRKCH | P24723 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19159123 | 0.79 | AAK1 (0.45) | LATS1LATS2CDC7KDM4C | |
| SCHEMBL26711507 | 0.79 | KDM4C (0.43) | LATS1LATS2CDC7KDM4CKDM4E | |
| SCHEMBL18343109 | 0.72 | CDC7 (0.43) | LATS1LATS2CDC7KDM4CKDM4E | |
| SCHEMBL19158203 | 0.71 | NAMPT (0.33) | LATS1LATS2KDM4C | |
| SCHEMBL17503742 | 0.71 | LATS1 (0.44) | LATS1LATS2CDC7KDM4C | |
| SCHEMBL19158707 | 0.70 | F7 (0.40) | LATS1KDM4E | |
| SCHEMBL15645596 | 0.69 | CDC7 (0.41) | LATS1LATS2CDC7KDM4CKDM4E | |
| SCHEMBL15645590 | 0.69 | CDC7 (0.41) | LATS1LATS2CDC7KDM4CKDM4E | |
| SCHEMBL16908309 | 0.69 | CDC7 (0.41) | LATS1LATS2CDC7KDM4CKDM4E | |
| SCHEMBL19158877 | 0.69 | KDM4C (0.40) | LATS1LATS2KDM4CKDM4EMAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970211-B1 | HISTONE DEMETHYLASE INHIBITORS | QUANTICEL PHARMACEUTICALS INC (US) | 2017-07-26 | — | — | EP | disclosed |