Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.40 |
| ▸ | LATS1 | O95835 | 5/20 | 0.34 |
| ▸ | LATS2 | Q9NRM7 | 4/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19158965 | 0.81 | KDM4C (0.40) | KDM4CLATS1LATS2CSNK2A2CSNK2B | |
| SCHEMBL17503811 | 0.78 | KDM4C (0.42) | KDM4CCSNK2A2KDM4E | |
| SCHEMBL19158706 | 0.76 | CA2 (0.45) | KDM4EL3MBTL1 | |
| SCHEMBL26711507 | 0.75 | KDM4C (0.43) | KDM4CLATS1LATS2KDM4EMAPKAPK2 | |
| SCHEMBL19159123 | 0.70 | AAK1 (0.45) | KDM4CLATS1LATS2 | |
| SCHEMBL20927237 | 0.70 | TDP1 (0.54) | TDP1L3MBTL1 | |
| SCHEMBL19158707 | 0.69 | F7 (0.40) | LATS1KDM4E | |
| SCHEMBL20724165 | 0.69 | KDM4C (0.57) | KDM4CTRPV1L3MBTL1 | |
| SCHEMBL19158367 | 0.69 | LATS1 (0.39) | KDM4CLATS1LATS2KDM4EMAPKAPK2 | |
| SCHEMBL22163584 | 0.68 | KDM4C (0.59) | KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970211-B1 | HISTONE DEMETHYLASE INHIBITORS | QUANTICEL PHARMACEUTICALS INC (US) | 2017-07-26 | — | — | EP | disclosed |