Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.45 |
| ▸ | LATS1 | O95835 | 14/20 | 0.40 |
| ▸ | LATS2 | Q9NRM7 | 13/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26711507 | 0.80 | KDM4C (0.43) | LATS1LATS2KDM4CCDC7 | |
| SCHEMBL19158367 | 0.79 | LATS1 (0.39) | LATS1LATS2KDM4CCDC7 | |
| SCHEMBL17503791 | 0.76 | LATS1 (0.38) | LATS1LATS2KDM4C | |
| SCHEMBL17503666 | 0.72 | KDM4C (0.42) | LATS1LATS2KDM4C | |
| SCHEMBL16908309 | 0.71 | CDC7 (0.41) | LATS1LATS2KDM4CCDC7 | |
| SCHEMBL18343109 | 0.70 | CDC7 (0.43) | LATS1LATS2KDM4CCDC7 | |
| SCHEMBL17517199 | 0.70 | KDM4C (0.39) | LATS1LATS2KDM4CCDC7 | |
| SCHEMBL19158877 | 0.70 | KDM4C (0.40) | LATS1LATS2KDM4C | |
| SCHEMBL19158203 | 0.69 | NAMPT (0.33) | LATS1LATS2KDM4C | |
| SCHEMBL19158870 | 0.69 | LATS1 (0.41) | AAK1LATS1LATS2KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970211-B1 | HISTONE DEMETHYLASE INHIBITORS | QUANTICEL PHARMACEUTICALS INC (US) | 2017-07-26 | — | — | EP | disclosed |