Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 19/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 19/20 | 0.43 |
| ▸ | ITGAL | P20701 | 19/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19158403 | 0.90 | ITGB2 (0.54) | ITGB2ICAM1ITGAL | |
| SCHEMBL16270928 | 0.89 | ITGB2 (0.57) | ITGB2ICAM1ITGAL | |
| SCHEMBL19158602 | 0.89 | ITGB2 (0.57) | ITGB2ICAM1ITGAL | |
| SCHEMBL16270927 | 0.89 | ITGB2 (0.51) | ITGB2ICAM1ITGAL | |
| SCHEMBL22296809 | 0.89 | ITGB2 (0.57) | ITGB2ICAM1ITGAL | |
| SCHEMBL23153576 | 0.89 | ITGB2 (0.57) | ITGB2ICAM1ITGAL | |
| SCHEMBL19157704 | 0.81 | ITGB2 (0.51) | ITGB2ICAM1ITGAL | |
| SCHEMBL4756049 | 0.81 | ITGB2 (0.53) | ITGB2ICAM1ITGAL | |
| SCHEMBL12054525 | 0.81 | ITGB2 (0.53) | ITGB2ICAM1ITGAL | |
| SCHEMBL22296929 | 0.80 | ITGB2 (0.53) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230233551-A1 | COMPOSITIONS AND METHODS FOR TREATMENT | CITIBANK, N.A., AS NOTES COLLATERAL AGENT | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230233551-A1 | COMPOSITIONS AND METHODS FOR TREATMENT | ICAM1, VCAM1, ITGAL | ITGB2 8/4885ICAM1 1/4885ITGAL 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.