Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | ATM | Q13315 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | STAT1 | P42224 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12221079 | 0.85 | KMT2A (0.59) | KMT2AMEN1MAPTALDH1A1ATM | |
| SCHEMBL19158900 | 0.84 | NPC1 (0.56) | ALDH1A1MAOBHPGDKDM4EHSD17B10 | |
| SCHEMBL27099971 | 0.84 | KMT2A (0.57) | KMT2AMEN1MAPTALDH1A1ATM | |
| SCHEMBL21806091 | 0.83 | ALDH1A1 (0.52) | KMT2AMEN1MAPTALDH1A1ATM | |
| SCHEMBL17737793 | 0.82 | KMT2A (0.65) | KMT2AMEN1MAPTALDH1A1ATM | |
| SCHEMBL13521824 | 0.82 | ALDH1A1 (0.60) | KMT2AMEN1MAPTALDH1A1ATM | |
| SCHEMBL22473845 | 0.81 | KMT2A (0.64) | KMT2AMEN1MAPTALDH1A1ATM | |
| SCHEMBL28625138 | 0.81 | GBA1 (0.52) | KMT2AMEN1MAPTALDH1A1ATM | |
| SCHEMBL17742665 | 0.81 | KMT2A (0.65) | KMT2AMEN1MAPTALDH1A1ATM | |
| SCHEMBL13403918 | 0.80 | KMT2A (0.71) | KMT2AMEN1MAPTALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303908-B1 | FLUORESCENT CYCLIC PEPTIDES, METHODS FOR THE PREPARATION THEREOF, AND USE OF SAID PEPTIDES FOR MEASURING THE ENZYMATIC ACTIVITY OF A PROTEASE ENZYME | COMMISSARIAT L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2017-07-26 | — | — | EP | disclosed |