⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2289059 | 0.85 | — | — | |
| SCHEMBL441763 | 0.81 | — | — | |
| SCHEMBL2289049 | 0.81 | — | — | |
| SCHEMBL27754359 | 0.75 | LOXL2 (0.32) | — | |
| SCHEMBL2291523 | 0.75 | GABRA1 (0.38) | — | |
| SCHEMBL2285493 | 0.75 | MAPT (0.32) | — | |
| SCHEMBL2288994 | 0.73 | — | — | |
| SCHEMBL17514595 | 0.69 | — | — | |
| SCHEMBL2286303 | 0.69 | — | — | |
| SCHEMBL2286037 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118063359-B | Binary asymmetric organic lithium salt, electrolyte and lithium battery | 蓝固(湖州)新能源科技有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118063359-A | Binary asymmetric organic lithium salt, electrolyte and lithium battery | 蓝固(湖州)新能源科技有限公司 | 2024-05-24 | — | — | CN | claimed |
| US-20200345735-A1 | HYDROXYLATED AND METHOXYLATED PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2020-11-05 | — | — | US | claimed |
| CN-110092788-A | Substituted [1,2,4] triazol [1,5-a] pyrimidin-7-yl compound as PDE2 inhibitor | 达特神经科学(开曼)有限公司 | 2019-08-06 | — | — | CN | claimed |
| CN-108250107-A | Cathepsin inhibitors and its preparation method and application | 沈阳药科大学 | 2018-07-06 | — | — | CN | claimed |
| CN-105073715-B | The derovatives of dihydrogen dazin 3,5 | 中外制药株式会社 | 2017-12-01 | — | — | CN | claimed |
| CN-107072993-A | Medicine containing sodium dependence phosphate transporter inhibitor | 中外制药株式会社 | 2017-08-18 | — | — | CN | claimed |
| CN-104428289-B | As the triazole compounds of antivirotic | 弗·哈夫曼-拉罗切有限公司 | 2017-06-23 | — | — | CN | claimed |
| US-9359340-B2 | Hydroxylated and methoxylated pyrimidyl cyclopentanes as Akt protein kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2016-06-07 | — | — | US | claimed |
| US-9303040-B2 | Substituted piperazines as AKT inhibitors | ARRAY BIOPHARMA INC. (US) | 2016-04-05 | — | — | US | claimed |
| US-20120232055-A1 | HYDROXYLATED AND METHOXYLATED PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS | GENENTECH, INC. (US) | 2012-09-13 | — | — | US | claimed |
| US-8063050-B2 | Hydroxylated and methoxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2011-11-22 | — | — | US | claimed |
| EP-2054418-B1 | DIHYDROTHIENO PYRIMIDINES AS AKT PROTEIN KINASE INHIBITORS | ARRAY BIOPHARMA INC (US) | 2011-11-09 | — | — | EP | claimed |
| US-20110269773-A1 | DIHYDROFURO PYRIMIDINES AS AKT PROTEIN KINASE INHIBITORS | ARRAY BIOPHARMA, INC. | 2011-11-03 | — | — | US | claimed |
| EP-2049501-B1 | HYDROXYLATED AND METHOXYLATED CYCLOPENTA [D] PYRIMIDINES AS AKT PROTEIN KINASE INHIBITORS | ARRAY BIOPHARMA INC (US) | 2011-09-14 | — | — | EP | claimed |
| EP-2049546-B1 | DIHYDROFURO PYRIMIDINES AS AKT PROTEIN KINASE INHIBITORS | ARRAY BIOPHARMA INC (US) | 2010-12-29 | — | — | EP | claimed |
| EP-2054418-A1 | DIHYDROTHIENO PYRIMIDINES AS AKT PROTEIN KINASE INHIBITORS | Array Biopharma, Inc. (US) | 2009-05-06 | — | — | EP | claimed |
| EP-2049546-A1 | DIHYDROFURO PYRIMIDINES AS AKT PROTEIN KINASE INHIBITORS | Array Biopharma, Inc. (US) | 2009-04-22 | — | — | EP | claimed |
| WO-2008006039-A1 | DIHYDROTHIENO PYRIMIDINES AS AKT PROTEIN KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2008-01-10 | — | — | WO | claimed |
| WO-2008006025-A1 | DIHYDROFURO PYRIMIDINES AS AKT PROTEIN KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2008-01-10 | — | — | WO | claimed |