SCHEMBL19167271

SCHEMBL19167271

c1ccc(-c2ccc(N(c3ccc(-c4ccc5c(c4)C4(c6ccccc6-c6ccccc6-c6ccccc64)c4ccccc4-5)cc3)c3ccc4c(c3)c3ccccc3n4-c3ccccc3)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TSPO P30536 2/20 0.36
PDK2 Q15119 2/20 0.35
HDAC4 P56524 1/20 0.30
KMT2A Q03164 1/20 0.30
IL1R1 P14778 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19167913 0.97 L3MBTL1 (0.39) KDM4EATML3MBTL1TSPOPDK2
SCHEMBL19166136 0.97 L3MBTL1 (0.39) KDM4EATML3MBTL1TSPOPDK2
SCHEMBL24976769 0.96 KDM4E (0.37) KDM4EATML3MBTL1TSPOPDK2
SCHEMBL19530840 0.96 TSPO (0.39) KDM4EATML3MBTL1TSPOPDK2
SCHEMBL24904877 0.96 KDM4E (0.38) KDM4EATML3MBTL1TSPOPDK2
SCHEMBL13775013 0.96 KDM4E (0.38) KDM4EATML3MBTL1TSPOPDK2
SCHEMBL23595012 0.96 L3MBTL1 (0.40) KDM4EATML3MBTL1TSPOPDK2
SCHEMBL12560106 0.96 L3MBTL1 (0.40) KDM4EATML3MBTL1TSPOPDK2
SCHEMBL13803233 0.95 KDM4E (0.38) KDM4EATML3MBTL1TSPOPDK2
SCHEMBL13775015 0.95 KDM4E (0.38) KDM4EATML3MBTL1TSPOPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10431751-B2 Compound and organic electronic device comprising the same SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) 2019-10-01 US disclosed
US-20170213970-A1 Novel compound and organic electronic device comprising the same SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) 2017-07-27 US disclosed
US-20170213970-A1 Novel compound and organic electronic device comprising the same SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) 2017-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10431751-B2 Compound and organic electronic device comprising the same CHRM1, CHRM2, ESR1 KDM4E 901/4885ATM 1462/4885L3MBTL1 672/4885
US-20170213970-A1 Novel compound and organic electronic device comprising the same CHRM1, CHRM2, ESR1 KDM4E 965/4885ATM 1235/4885L3MBTL1 734/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.