Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | TNKS | O95271 | 2/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19169424 | 0.90 | HRH4 (0.43) | HRH4MEN1KMT2ANPSR1MAPT | |
| SCHEMBL19161195 | 0.83 | HRH4 (0.37) | HRH4MEN1KMT2ANPSR1MAPT | |
| SCHEMBL22211877 | 0.79 | PIK3CA (0.36) | HRH4HTR2CPIK3CA | |
| SCHEMBL22652159 | 0.78 | HRH4 (0.34) | HRH4HTR2CPIK3CA | |
| SCHEMBL19169920 | 0.77 | MAPT (0.39) | HRH4MEN1KMT2ANPSR1MAPT | |
| SCHEMBL21031413 | 0.76 | NPC1 (0.34) | HRH4MEN1KMT2ANPSR1MAPT | |
| SCHEMBL20670230 | 0.76 | KDM4E (0.34) | HRH4HTR2CKDM4ETNKSTNKS2 | |
| SCHEMBL19161853 | 0.76 | HRH4 (0.33) | HRH4HTR2CPIK3CA | |
| SCHEMBL19162446 | 0.76 | HRH4 (0.33) | HRH4HTR2CPIK3CA | |
| SCHEMBL19162142 | 0.76 | HRH4 (0.33) | HRH4HTR2CPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10347845-B2 | Nitrogen-containing condensed cyclic compound and organic light emitting device using same | LG CHEM, LTD. (KR) | 2019-07-09 | — | — | US | disclosed |
| US-20170213984-A1 | NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME | LG CHEM, LTD. (KR) | 2017-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10347845-B2 | Nitrogen-containing condensed cyclic compound and organic light emitting device using same | CRY1, NOS1, NOLC1 | HRH4 1225/4885MEN1 197/4885KMT2A 1423/4885 |
| US-20170213984-A1 | NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME | CRY1, NOS1, NOLC1 | HRH4 1225/4885MEN1 197/4885KMT2A 1423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.