SCHEMBL19169883

SCHEMBL19169883

Cc1nc(-c2cc3ccccc3c3ccccc23)nc2ccccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.53
CYP1A2 P05177 7/20 0.49
ALDH1A1 P00352 3/20 0.49
HSD17B10 Q99714 2/20 0.49
HPGD P15428 1/20 0.49
NUDT1 P36639 1/20 0.49
PDE10A Q9Y233 3/20 0.46
CYP2D6 P10635 3/20 0.43
CLK4 Q9HAZ1 3/20 0.43
CYP2C19 P33261 3/20 0.43
CYP3A4 P08684 3/20 0.43
TSHR P16473 2/20 0.43
MAPK1 P28482 2/20 0.43
USP2 O75604 1/20 0.43
ALOX15 P16050 1/20 0.43
KDM4E B2RXH2 1/20 0.42
MPO P05164 1/20 0.41
RAD52 P43351 1/20 0.41
CYP1A1 P04798 1/20 0.41
CYP1B1 Q16678 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21174591 0.79 METAP1 (0.57) CYP1A2ALDH1A1HSD17B10HPGDCYP2D6
SCHEMBL13314087 0.79 CYP11B1 (0.52) CYP1A2ALDH1A1HSD17B10HPGDCYP2D6
SCHEMBL19169797 0.79 PDE10A (0.56) GPR3CYP1A2ALDH1A1HSD17B10HPGD
SCHEMBL19161951 0.79 CYP11B1 (0.37) GPR3CYP1A2HSD17B10HPGDCYP2D6
SCHEMBL20233977 0.77 CYP1A2 (0.50) GPR3CYP1A2ALDH1A1HSD17B10HPGD
SCHEMBL19169769 0.77 PDE10A (0.57) GPR3CYP1A2ALDH1A1HSD17B10HPGD
SCHEMBL13674005 0.76 KMT2A (0.60) HPGDTSHR
SCHEMBL13984387 0.76 CYP1A2 (0.65) CYP1A2ALDH1A1HSD17B10CYP2D6CLK4
SCHEMBL2606209 0.76 CYP1A2 (0.58) GPR3CYP1A2ALDH1A1HSD17B10HPGD
SCHEMBL422358 0.76 PDE10A (0.61) GPR3CYP1A2ALDH1A1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170213984-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME LG CHEM, LTD. (KR) 2017-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170213984-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME CRY1, NOS1, NOLC1 GPR3 3632/4885CYP1A2 667/4885ALDH1A1 331/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.