Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 18/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 11/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17447562 | 1.00 | OPRM1 (0.46) | OPRM1OPRL1EPHX2 | |
| Hydrochloric Acid SCHEMBL17444140 | 0.99 | OPRM1 (0.46) | OPRM1OPRL1EPHX2 | |
| Hydrochloric Acid SCHEMBL17444137 | 0.99 | OPRM1 (0.46) | OPRM1OPRL1EPHX2 | |
| Hydrochloric Acid SCHEMBL17443990 | 0.94 | OPRM1 (0.44) | OPRM1OPRL1EPHX2 | |
| SCHEMBL17447502 | 0.94 | OPRM1 (0.48) | OPRM1OPRL1EPHX2 | |
| Hydrochloric Acid SCHEMBL17443962 | 0.93 | OPRM1 (0.47) | OPRM1OPRL1EPHX2 | |
| Hydrochloric Acid SCHEMBL17443961 | 0.93 | OPRM1 (0.47) | OPRM1OPRL1EPHX2 | |
| SCHEMBL17444166 | 0.92 | OPRM1 (0.44) | OPRM1OPRL1 | |
| SCHEMBL17444164 | 0.92 | OPRM1 (0.44) | OPRM1OPRL1 | |
| SCHEMBL17443848 | 0.89 | OPRM1 (0.45) | OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170210734-A1 | Substituted Azaspiro(4.5)Decane Derivatives | GRUENENTHAL GMBH (DE) | 2017-07-27 | — | — | US | disclosed |
| US-20170210734-A1 | Substituted Azaspiro(4.5)Decane Derivatives | GRUENENTHAL GMBH (DE) | 2017-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170210734-A1 | Substituted Azaspiro(4.5)Decane Derivatives | OPRL1, OPRM1, OPRD1 | OPRM1 2/4885OPRL1 1/4885EPHX2 3509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.