Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | ATG7 | O95352 | 8/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.46 |
| ▸ | METTL3 | Q86U44 | 3/20 | 0.46 |
| ▸ | ADK | P55263 | 3/20 | 0.46 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20643708 | 0.93 | CA2 (0.52) | CA2ATG7PRMT5METTL3ADK | |
| SCHEMBL19625183 | 0.93 | CA2 (0.52) | CA2ATG7PRMT5METTL3ADK | |
| SCHEMBL19519733 | 0.89 | CA2 (0.51) | CA2ATG7PRMT5METTL3ADK | |
| SCHEMBL25469568 | 0.85 | CA2 (0.49) | CA2ATG7PRMT5METTL3ADK | |
| SCHEMBL21585107 | 0.85 | CA2 (0.49) | CA2PRMT5METTL3ADK | |
| SCHEMBL6061656 | 0.85 | CA2 (0.49) | CA2PRMT5METTL3ADK | |
| SCHEMBL2611617 | 0.82 | CA2 (0.52) | CA2ATG7PRMT5METTL3ADK | |
| SCHEMBL15355732 | 0.82 | CA2 (0.43) | CA2ATG7PRMT5METTL3ADK | |
| SCHEMBL22386564 | 0.80 | CA2 (0.53) | CA2ATG7PRMT5METTL3ADK | |
| SCHEMBL18214123 | 0.79 | ADK (0.51) | CA2PRMT5METTL3ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867255-B1 | METHOD FOR THE SELECTION AND PRODUCTION OF TAILOR-MADE, SELECTIVE AND MULTI-SPECIFIC THERAPEUTIC MOLECULES COMPRISING AT LEAST TWO DIFFERENT TARGETING ENTITIES AND USES THEREOF | HOFFMANN LA ROCHE (CH) | 2017-07-19 | — | — | EP | disclosed |