Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 13/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19149452 | 1.00 | KMT2A (0.54) | KMT2AMEN1EPHX2EPHX1ALDH1A1 | |
| SCHEMBL19148934 | 0.86 | EPHX2 (0.61) | KMT2AMEN1EPHX2EPHX1ALDH1A1 | |
| SCHEMBL19173466 | 0.84 | KMT2A (0.50) | KMT2AMEN1EPHX2ALDH1A1HPGD | |
| SCHEMBL19173946 | 0.84 | EPHX2 (0.43) | KMT2AMEN1EPHX2EPHX1GRIN2D | |
| SCHEMBL24139700 | 0.81 | LMNA (0.55) | KMT2AMEN1ALDH1A1GRIN2DGRIN3B | |
| SCHEMBL24139659 | 0.81 | LMNA (0.55) | KMT2AMEN1ALDH1A1GRIN2DGRIN3B | |
| SCHEMBL19173532 | 0.79 | KMT2A (0.57) | KMT2AMEN1EPHX2ALDH1A1HPGD | |
| SCHEMBL4212248 | 0.79 | KMT2A (0.60) | KMT2AMEN1EPHX2ALDH1A1HPGD | |
| SCHEMBL6508475 | 0.77 | EPHX2 (0.73) | EPHX2EPHX1 | |
| SCHEMBL29327072 | 0.77 | GRIN2D (0.47) | KMT2AMEN1ALDH1A1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017127306-A1 | ADAMATANE DERIVATIVES FOR THE TREATMENT OF FILOVIRUS INFECTION | ARISAN THERAPEUTICS (US) | 2017-07-27 | — | — | WO | disclosed |