Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.55 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.55 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.55 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.55 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.55 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4212248 | 0.88 | KMT2A (0.60) | KMT2AMEN1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL4215171 | 0.82 | KMT2A (0.51) | KMT2AMEN1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL19173466 | 0.81 | KMT2A (0.50) | KMT2AMEN1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL19149452 | 0.79 | KMT2A (0.54) | KMT2AMEN1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL19172941 | 0.79 | KMT2A (0.54) | KMT2AMEN1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL19173222 | 0.78 | KMT2A (0.47) | KMT2AMEN1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL13878591 | 0.78 | EPHX2 (0.47) | KMT2AMEN1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL19148485 | 0.78 | HSD11B1 (0.63) | KMT2AMEN1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL4216875 | 0.77 | GAA (0.51) | KMT2AMEN1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL13878649 | 0.77 | GAA (0.51) | KMT2AMEN1GRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017127306-A1 | ADAMATANE DERIVATIVES FOR THE TREATMENT OF FILOVIRUS INFECTION | ARISAN THERAPEUTICS (US) | 2017-07-27 | — | — | WO | disclosed |