Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.32 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.32 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.32 |
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.32 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18851707 | 0.79 | — | — | |
| SCHEMBL20613232 | 0.77 | RXFP1 (0.42) | KDM4ERAB9ATSHRCASP1KMT2A | |
| SCHEMBL14532156 | 0.76 | CHRM2 (0.37) | KMT2AALDH1A1 | |
| SCHEMBL9056185 | 0.73 | KMT2A (0.44) | KDM4ERAB9ATSHRCASP1KMT2A | |
| SCHEMBL23798668 | 0.72 | BTK (0.38) | KMT2AALDH1A1POLB | |
| SCHEMBL12779155 | 0.72 | ALDH1A1 (0.61) | KDM4ERAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL182243 | 0.72 | ALDH1A1 (0.61) | KDM4ERAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL573354 | 0.69 | ALDH1A1 (0.63) | KDM4ERAB9AKMT2AALDH1A1RXFP1 | |
| SCHEMBL10031678 | 0.69 | TSHR (0.43) | KDM4ERAB9ATSHRCASP1KMT2A | |
| SCHEMBL5233094 | 0.68 | ACHE (0.35) | KDM4ERAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017125506-A1 | ARYL SUBSTITUTED PYRIMIDINES FOR USE IN INFLUENZA VIRUS INFECTION | JANSSEN SCIENCES IRELAND UC (IE) | 2017-07-27 | — | — | WO | disclosed |