Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | F13A1 | P00488 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14012684 | 0.86 | ST14 (0.49) | ST14IDO1CA1CA2NPC1 | |
| SCHEMBL12363836 | 0.85 | ST14 (0.45) | ST14IDO1CA1CA2NPC1 | |
| SCHEMBL17777450 | 0.85 | KDM4E (0.50) | ST14IDO1CA2NPC1RAB9A | |
| SCHEMBL8441620 | 0.83 | IDO1 (0.60) | ST14IDO1CA1CA2NPC1 | |
| SCHEMBL17198835 | 0.83 | NPC1 (0.46) | ST14IDO1CA1CA2NPC1 | |
| SCHEMBL18624777 | 0.83 | ST14 (0.44) | ST14IDO1CA1CA2NPC1 | |
| SCHEMBL19176287 | 0.83 | ST14 (0.34) | ST14IDO1 | |
| Hydrochloric Acid SCHEMBL19371472 | 0.83 | KDM4E (0.49) | ST14IDO1NPC1RAB9ACYP2D6 | |
| SCHEMBL18624768 | 0.83 | NPC1 (0.49) | ST14IDO1CA1CA2NPC1 | |
| SCHEMBL17198796 | 0.83 | HPGD (0.46) | ST14IDO1CA1CA2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170210704-A1 | DEUTERO-PHENFORMIN DERIVATIVES | ENLIBRIUM, INC. | 2017-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170210704-A1 | DEUTERO-PHENFORMIN DERIVATIVES | PKD1, GLS, WFS1 | ST14 1516/4885IDO1 4361/4885CA1 4163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.