Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 5/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17447478 | 0.89 | CETP (0.34) | CETP | |
| SCHEMBL11359161 | 0.85 | CETP (0.44) | CETPSPHK1CYP4F2CYP4A11 | |
| SCHEMBL12273347 | 0.85 | CETP (0.36) | CETPSPHK1CYP4F2CYP4A11 | |
| SCHEMBL1858688 | 0.83 | CETP (0.47) | CETPSPHK1CYP4F2CYP4A11 | |
| SCHEMBL11299798 | 0.83 | CETP (0.47) | CETPSPHK1CYP4F2CYP4A11 | |
| Hydrochloric Acid SCHEMBL28085803 | 0.81 | CETP (0.46) | CETPSPHK1CYP4F2CYP4A11 | |
| SCHEMBL12273729 | 0.81 | CETP (0.41) | CETPSPHK1CYP4F2CYP4A11 | |
| SCHEMBL613082 | 0.79 | CYP4F2 (0.38) | CETPSPHK1CYP4F2CYP4A11 | |
| SCHEMBL5027335 | 0.78 | CYP4F2 (0.46) | CETPSPHK1CYP4F2CYP4A11 | |
| SCHEMBL19169733 | 0.77 | CYP2D6 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170210734-A1 | Substituted Azaspiro(4.5)Decane Derivatives | GRUENENTHAL GMBH (DE) | 2017-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170210734-A1 | Substituted Azaspiro(4.5)Decane Derivatives | OPRL1, OPRM1, OPRD1 | CETP 3514/4885SPHK1 2551/4885POLB 4050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.