Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.42 |
| ▸ | CTSK | P43235 | 5/20 | 0.42 |
| ▸ | CTSB | P07858 | 4/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | REN | P00797 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19177405 | 1.00 | CTSS (0.42) | CTSSCTSKCTSBPPARGPPARA | |
| SCHEMBL19177395 | 0.91 | CTSS (0.41) | CTSSCTSKCTSBPPARGPPARA | |
| SCHEMBL19177394 | 0.91 | CTSS (0.41) | CTSSCTSKCTSBPPARGPPARA | |
| SCHEMBL15873885 | 0.90 | CTSS (0.44) | CTSSCTSKCTSBPPARGPPARA | |
| SCHEMBL19178279 | 0.89 | CTSS (0.42) | CTSSCTSKCTSBPPARGPPARA | |
| SCHEMBL15886472 | 0.89 | CTSS (0.42) | CTSSCTSKCTSBPPARGPPARA | |
| SCHEMBL19177409 | 0.89 | CTSS (0.45) | CTSSCTSKCTSBPPARGPPARA | |
| SCHEMBL15886484 | 0.89 | CTSS (0.45) | CTSSCTSKCTSBPPARGPPARA | |
| SCHEMBL15886481 | 0.88 | CTSL (0.46) | CTSSCTSKCTSBPPARGPPARA | |
| SCHEMBL15915584 | 0.88 | CTSL (0.46) | CTSSCTSKCTSBPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2943493-B1 | THERAPEUTIC COMPOUNDS FOR THE TREATMENT OF VIRAL INFECTIONS | GILEAD SCIENCES INC (US) | 2017-08-02 | — | — | EP | disclosed |