Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ESRRB | O95718 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19182066 | 1.00 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HTTALOX15HPGD | |
| SCHEMBL17505998 | 1.00 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HTTALOX15HPGD | |
| SCHEMBL17506006 | 1.00 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HTTALOX15HPGD | |
| SCHEMBL17505994 | 0.91 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2HTTHPGDPSMB1 | |
| SCHEMBL17505992 | 0.91 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2HTTHPGDPSMB1 | |
| SCHEMBL17506009 | 0.89 | SMN1; SMN2 (0.54) | ALDH1A1SMN1; SMN2HTTALOX15HPGD | |
| SCHEMBL19181028 | 0.89 | SMN1; SMN2 (0.54) | ALDH1A1SMN1; SMN2HTTALOX15HPGD | |
| SCHEMBL17506001 | 0.89 | SMN1; SMN2 (0.54) | ALDH1A1SMN1; SMN2HTTALOX15HPGD | |
| SCHEMBL19181332 | 0.89 | SMN1; SMN2 (0.54) | ALDH1A1SMN1; SMN2HTTALOX15HPGD | |
| SCHEMBL17524185 | 0.85 | ESR1 (0.58) | PSMB1PSMB5MAPTESRRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170217914-A1 | Novel Triarylethylene Compounds and Methods Using Same | THE PENN STATE RESEARCH FOUNDATION | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217914-A1 | Novel Triarylethylene Compounds and Methods Using Same | CYP46A1, GSTA2, GSTA1 | ALDH1A1 176/4885SMN1; SMN2 3107/4885HTT 1424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.