SCHEMBL19181541

SCHEMBL19181541

CNC(=O)Cc1cccc(CCI)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
MTNR1A P48039 1/20 0.43
MTNR1B P49286 1/20 0.43
KMT2A Q03164 4/20 0.42
CYP4F2 P78329 1/20 0.41
CYP4A11 Q02928 1/20 0.41
HPGD P15428 3/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
CASP1 P29466 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MEN1 O00255 3/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HDAC8 Q9BY41 2/20 0.40
HDAC1 Q13547 1/20 0.40
GAA P10253 2/20 0.39
PCNA P12004 1/20 0.39
NLRP3 Q96P20 1/20 0.38
GLS O94925 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19182347 0.87 FFAR1 (0.49) ALDH1A1MTNR1AMTNR1BCYP4F2CYP4A11
SCHEMBL15433150 0.85 TRPV1 (0.54) ALDH1A1MTNR1AMTNR1BKMT2AHPGD
SCHEMBL13501581 0.81 KMT2A (0.50) MTNR1AMTNR1BKMT2ACYP4F2CYP4A11
SCHEMBL23547266 0.79 GLS (0.52) ALDH1A1CYP4F2CYP4A11SMN1; SMN2GLS
SCHEMBL28634642 0.79 MAPK8 (0.52) KMT2ACYP4F2CYP4A11MEN1SMN1; SMN2
Hydrochloric Acid SCHEMBL20187060 0.78 GLS (0.51) ALDH1A1CYP4F2CYP4A11SMN1; SMN2GLS
SCHEMBL19155988 0.78 SLC7A5 (0.43) KMT2ACYP4F2CYP4A11MEN1PCNA
SCHEMBL7342803 0.77 CTBP2 (0.51) ALOX15NLRP3HDAC6
SCHEMBL13329815 0.77 L3MBTL1 (0.56) ALDH1A1KMT2AHPGDMEN1GAA
SCHEMBL24500947 0.77 SLC7A5 (0.46) KMT2ACYP4F2CYP4A11MEN1HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9715187-B2 Method of producing a compound having a colorant structure, and toner containing a compound obtained by the production method CANON KABUSHIKI KAISHA (JP) 2017-07-25 US disclosed