Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11266430 | 0.75 | PTPN1 (0.56) | ALDH1A1POLBKMT2ATDP1PTPN1 | |
| SCHEMBL19182281 | 0.74 | PTPN1 (0.59) | ALDH1A1POLBKMT2APTPN1 | |
| SCHEMBL19196720 | 0.73 | IDO1 (0.37) | ALDH1A1POLBKMT2ATDP1GPR35 | |
| SCHEMBL19180090 | 0.73 | ALDH1A1 (0.42) | ALDH1A1POLBKMT2ATDP1PTPN1 | |
| SCHEMBL19182258 | 0.72 | ALDH1A1 (0.44) | ALDH1A1POLBKMT2ATDP1PTPN1 | |
| SCHEMBL13978666 | 0.71 | ALDH1A1 (0.58) | ALDH1A1POLBKMT2ATDP1PTPN1 | |
| SCHEMBL19182080 | 0.70 | ALDH1A1 (0.56) | ALDH1A1PTPN1 | |
| SCHEMBL19182079 | 0.70 | ALDH1A1 (0.56) | ALDH1A1PTPN1 | |
| SCHEMBL30947812 | 0.69 | ALDH1A1 (0.55) | ALDH1A1POLBKMT2ATDP1 | |
| SCHEMBL10991271 | 0.69 | PTPN1 (0.56) | ALDH1A1POLBKMT2ATDP1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3407974-A1 | AMLEXANOX ANALOGS | The Regents Of The University Of Michigan (US) | 2018-12-05 | — | — | EP | disclosed |
| US-20170217980-A1 | AMLEXANOX ANALOGS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2017-08-03 | — | — | US | disclosed |
| US-20170217980-A1 | AMLEXANOX ANALOGS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2017-08-03 | — | — | US | disclosed |
| US-20170217980-A1 | AMLEXANOX ANALOGS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2017-08-03 | — | — | US | disclosed |
| WO-2017132538-A1 | AMLEXANOX ANALOGS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2017-08-03 | — | — | WO | disclosed |
| WO-2017132538-A1 | AMLEXANOX ANALOGS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2017-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217980-A1 | AMLEXANOX ANALOGS | GPR119, GLP1R, IRS1 | ALDH1A1 1946/4885POLB 3771/4885KMT2A 2197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.