Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.35 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | TPO | P07202 | 1/20 | 0.34 |
| ▸ | EPX | P11678 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22778534 | 0.83 | DHFR (0.35) | KDM4ENPC1RAB9ATSHRCNR1 | |
| SCHEMBL22752635 | 0.83 | DHFR (0.35) | KDM4ENPC1RAB9ATSHRCNR1 | |
| SCHEMBL19252971 | 0.83 | DHFR (0.35) | KDM4ENPC1RAB9ATSHRCNR1 | |
| SCHEMBL19251052 | 0.83 | DHFR (0.35) | KDM4ENPC1RAB9ATSHRCNR1 | |
| SCHEMBL19184867 | 0.80 | MEN1 (0.38) | KDM4ENR5A1ALDH1A1HPGDHTT | |
| SCHEMBL22752366 | 0.78 | CNR2 (0.33) | KDM4ENR5A1TSHRCNR1CNR2 | |
| SCHEMBL22778499 | 0.78 | CNR2 (0.33) | KDM4ENR5A1TSHRCNR1CNR2 | |
| SCHEMBL19251374 | 0.78 | CNR2 (0.33) | KDM4ENR5A1TSHRCNR1CNR2 | |
| SCHEMBL31538780 | 0.78 | NR5A1 (0.53) | KDM4ENPC1RAB9AMCHR1NR5A1 | |
| SCHEMBL19251172 | 0.77 | CNR2 (0.32) | KDM4ENR5A1TSHRCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9718825-B2 | N-(4-(azaindazol-6-yl)-phenyl)-sulfonamides and their use as pharmaceuticals | SANOFI (FR) | 2017-08-01 | — | — | US | disclosed |