Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 4/20 | 0.34 |
| ▸ | CNR2 | P34972 | 4/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19184855 | 0.80 | KDM4E (0.37) | CNR1CNR2KDM4EALDH1A1HPGD | |
| SCHEMBL19184890 | 0.80 | CNR2 (0.38) | CNR1CNR2KDM4E | |
| SCHEMBL19251172 | 0.78 | CNR2 (0.32) | CNR1CNR2KDM4ENR5A1 | |
| SCHEMBL19184871 | 0.78 | CNR2 (0.39) | CNR1CNR2KDM4E | |
| SCHEMBL26449329 | 0.77 | MEN1 (0.39) | MEN1PABPC1KMT2ACNR1CNR2 | |
| SCHEMBL19252846 | 0.76 | CNR1 (0.30) | KMT2ACNR1CNR2 | |
| SCHEMBL22778499 | 0.76 | CNR2 (0.33) | CNR1CNR2KDM4ENR5A1 | |
| SCHEMBL22752366 | 0.76 | CNR2 (0.33) | CNR1CNR2KDM4ENR5A1 | |
| SCHEMBL19251374 | 0.76 | CNR2 (0.33) | CNR1CNR2KDM4ENR5A1 | |
| SCHEMBL22752635 | 0.75 | DHFR (0.35) | CNR1CNR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9718825-B2 | N-(4-(azaindazol-6-yl)-phenyl)-sulfonamides and their use as pharmaceuticals | SANOFI (FR) | 2017-08-01 | — | — | US | disclosed |