Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24507222 | 0.90 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2TP53PSMB5SIGMAR1 | |
| SCHEMBL25040447 | 0.86 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2SIGMAR1TDP1MEN1 | |
| SCHEMBL25964301 | 0.82 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2TP53SIGMAR1TDP1 | |
| SCHEMBL24590552 | 0.81 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2TP53SIGMAR1TDP1 | |
| SCHEMBL23824133 | 0.80 | SMN1; SMN2 (0.49) | ALDH1A1SMN1; SMN2TP53SIGMAR1TDP1 | |
| SCHEMBL21319581 | 0.80 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2SIGMAR1MEN1KMT2A | |
| SCHEMBL12327463 | 0.79 | HSD17B10 (0.39) | ALDH1A1SMN1; SMN2TDP1KDM4E | |
| SCHEMBL12327042 | 0.79 | HSD17B10 (0.39) | ALDH1A1SMN1; SMN2TDP1KDM4E | |
| SCHEMBL24540412 | 0.79 | HSD17B10 (0.39) | ALDH1A1SMN1; SMN2TDP1KDM4E | |
| SCHEMBL25576425 | 0.79 | HSD17B10 (0.39) | ALDH1A1SMN1; SMN2TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9717803-B2 | Enzymatic conjugation of polypeptides | INNATE PHARMA (FR) | 2017-08-01 | — | — | US | disclosed |