Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.34 |
| ▸ | PPIA | P62937 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744392 | 0.87 | P2RX7 (0.40) | P2RX7TSHRKMT2APPIAEPHX1 | |
| SCHEMBL28083977 | 0.84 | P2RX7 (0.41) | P2RX7CA12CA14KMT2AEPHX1 | |
| SCHEMBL28275818 | 0.83 | P2RX7 (0.39) | P2RX7CA12CA2CA14KMT2A | |
| SCHEMBL8282998 | 0.82 | CA12 (0.42) | P2RX7CA12CA2CA14KMT2A | |
| SCHEMBL28220352 | 0.82 | P2RX7 (0.40) | P2RX7EPHX1 | |
| SCHEMBL7272144 | 0.81 | P2RX7 (0.41) | P2RX7CA12CA2CA14KMT2A | |
| SCHEMBL9742297 | 0.81 | P2RX7 (0.41) | P2RX7CA12CA2CA14KMT2A | |
| SCHEMBL28210022 | 0.81 | P2RX7 (0.38) | P2RX7KMT2AEPHX2PPIAEPHX1 | |
| SCHEMBL7639921 | 0.81 | P2RX7 (0.42) | P2RX7CA12CA2CA14KMT2A | |
| SCHEMBL28816491 | 0.81 | P2RX7 (0.39) | P2RX7CA12CA2CA14KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3199530-A1 | BENZOFURAN ANALOGUE AS NS4B INHIBITOR | Changzhou Yinsheng Pharmaceutical Co., Ltd. (CN) | 2017-08-02 | — | — | EP | disclosed |