Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PPIA | P62937 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | SMO | Q99835 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7272144 | 1.00 | P2RX7 (0.41) | P2RX7EPHX1FOLH1BTKGAA | |
| SCHEMBL9742662 | 0.98 | P2RX7 (0.39) | P2RX7EPHX1FOLH1BTKGAA | |
| SCHEMBL22743593 | 0.92 | FOLH1 (0.36) | P2RX7EPHX1FOLH1BTKGAA | |
| SCHEMBL9744392 | 0.91 | P2RX7 (0.40) | P2RX7EPHX1FOLH1BTKGAA | |
| SCHEMBL5538732 | 0.85 | CTSL (0.34) | P2RX7FOLH1GAAMEN1KMT2A | |
| SCHEMBL7639921 | 0.84 | P2RX7 (0.42) | P2RX7EPHX1BTKGAAMEN1 | |
| SCHEMBL1162996 | 0.84 | P2RX7 (0.42) | P2RX7EPHX1BTKGAAMEN1 | |
| SCHEMBL9743498 | 0.83 | CTSK (0.34) | EPHX1FOLH1BTKGAAMEN1 | |
| SCHEMBL22960737 | 0.83 | P2RX7 (0.41) | P2RX7EPHX1BTKGAAMEN1 | |
| SCHEMBL27594406 | 0.82 | MEN1 (0.36) | P2RX7FOLH1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128448-A | Peptide hormones | HOFFMAN-LA ROCHE INC. (US) | 1992-07-07 | — | — | US | disclosed |