Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 3/20 | 0.37 |
| ▸ | APAF1 | O14727 | 2/20 | 0.32 |
| ▸ | UBE2N | P61088 | 2/20 | 0.32 |
| ▸ | IDE | P14735 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14602935 | 0.89 | CTSL (0.31) | — | |
| SCHEMBL19189308 | 0.86 | — | — | |
| SCHEMBL19188679 | 0.85 | APAF1 (0.31) | APAF1UBE2NIDERECQLNPSR1 | |
| SCHEMBL14602933 | 0.85 | CETP (0.44) | — | |
| SCHEMBL19188512 | 0.85 | — | — | |
| SCHEMBL14602936 | 0.85 | — | — | |
| SCHEMBL19188554 | 0.84 | CETP (0.30) | — | |
| SCHEMBL14602934 | 0.84 | CETP (0.36) | — | |
| SCHEMBL5628375 | 0.84 | TACR1 (0.33) | TACR1APAF1UBE2NIDERECQL | |
| SCHEMBL5624044 | 0.84 | CETP (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848430-B1 | NOVEL BENZYLAMINE DERIVATIVES AS CETP INHIBITORS | Dr Reddys Laboratories Ltd (IN) | 2017-08-02 | — | — | EP | disclosed |