Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19190655 | 0.88 | ALDH1A1 (0.63) | ALDH1A1LMNAKDM4EKMT2AMEN1 | |
| SCHEMBL29208032 | 0.83 | HTR2A (0.56) | ALDH1A1LMNAKDM4EKMT2AMEN1 | |
| SCHEMBL15033016 | 0.83 | ALDH1A1 (0.68) | ALDH1A1LMNAKDM4EKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL29208098 | 0.82 | HTR2A (0.55) | ALDH1A1LMNAKDM4EKMT2AMEN1 | |
| SCHEMBL15935698 | 0.81 | ALDH1A1 (0.94) | ALDH1A1LMNAKDM4EKMT2AMEN1 | |
| SCHEMBL15503835 | 0.80 | ALDH1A1 (0.97) | ALDH1A1LMNAKDM4EKMT2AMEN1 | |
| SCHEMBL6398848 | 0.80 | ALDH1A1 (0.62) | ALDH1A1LMNAKDM4EKMT2AMEN1 | |
| SCHEMBL16002873 | 0.79 | POLB (0.68) | ALDH1A1LMNAKMT2ASMN1; SMN2POLB | |
| SCHEMBL4874455 | 0.79 | ALDH1A1 (0.76) | ALDH1A1LMNAKDM4EKMT2AMEN1 | |
| SCHEMBL6402005 | 0.78 | ALDH1A1 (0.60) | ALDH1A1LMNAKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794595-B1 | HETEROCYCLIC COMPOUNDS, MEDICAMENTS CONTAINING SAID COMPOUNDS, USE THEREOF AND PROCESSES FOR THE PREPARATION THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2017-08-02 | — | — | EP | disclosed |