Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 16/20 | 0.70 |
| ▸ | FPR2 | P25090 | 10/20 | 0.70 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19195096 | 0.90 | GRM5 (0.78) | GRM5FPR2P2RX7 | |
| SCHEMBL11942897 | 0.90 | GRM5 (0.78) | GRM5FPR2P2RX7 | |
| SCHEMBL11028474 | 0.90 | GRM5 (0.78) | GRM5FPR2P2RX7 | |
| SCHEMBL10151945 | 0.89 | GRM5 (0.83) | GRM5FPR2P2RX7 | |
| SCHEMBL11942898 | 0.89 | GRM5 (0.79) | GRM5FPR2P2RX7 | |
| SCHEMBL11942896 | 0.89 | GRM5 (0.79) | GRM5FPR2P2RX7 | |
| SCHEMBL11028230 | 0.89 | GRM5 (0.79) | GRM5FPR2P2RX7 | |
| SCHEMBL11030478 | 0.88 | GRM5 (0.74) | GRM5FPR2IDO1 | |
| SCHEMBL11031284 | 0.88 | GRM5 (0.74) | GRM5FPR2IDO1 | |
| SCHEMBL11942881 | 0.85 | GRM5 (0.77) | GRM5FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170217950-A1 | Bicyclo[3.2.1]Octyl Amide Derivatives and Uses of Same | H. LUNDBECK A/S (DK) | 2017-08-03 | — | — | US | disclosed |
| US-20170217950-A1 | Bicyclo[3.2.1]Octyl Amide Derivatives and Uses of Same | H. LUNDBECK A/S (DK) | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217950-A1 | Bicyclo[3.2.1]Octyl Amide Derivatives and Uses of Same | SLC10A1, CLIC1, ABCB11 | GRM5 3148/4885FPR2 2633/4885IDO1 1609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.