SCHEMBL19195690

SCHEMBL19195690

CC(C)(C)c1c(O)c(O)c(O)c2ccccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA2 P00918 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ HTT P42858 1/20 0.39
▸ KDM4E B2RXH2 4/20 0.38
▸ MEN1 O00255 3/20 0.38
▸ MAPT P10636 3/20 0.38
▸ KMT2A Q03164 3/20 0.38
▸ MCL1 Q07820 3/20 0.38
▸ POLB P06746 2/20 0.38
▸ NSD2 O96028 1/20 0.38
▸ ALDH1A1 P00352 2/20 0.38
▸ TSHR P16473 2/20 0.38
▸ TDP1 Q9NUW8 2/20 0.38
▸ GAA P10253 1/20 0.37
▸ CACNA1B Q00975 1/20 0.37
▸ APBA1 Q02410 1/20 0.37
▸ PKM P14618 1/20 0.36
▸ THRB P10828 2/20 0.35
▸ CYP2C9 P11712 1/20 0.35
▸ HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14506247 0.91 CA2 (0.39) CA2LMNAHTTKDM4EMEN1
SCHEMBL11431265 0.83 LMNA (0.41) CA2LMNAHTTKDM4EMEN1
SCHEMBL19196660 0.79 CA2 (0.34) CA2LMNAHTTKDM4EMEN1
SCHEMBL30849704 0.77 CYP1A2 (0.40) CA2KDM4EALDH1A1TSHRTDP1
SCHEMBL29648165 0.77 IDO1 (0.53) CA2LMNAHTTKDM4EMEN1
SCHEMBL27740 0.77 IDO1 (0.53) CA2LMNAHTTKDM4EMEN1
SCHEMBL19203147 0.77 GLRA3 (0.47) HTTKDM4EMEN1MAPTKMT2A
SCHEMBL19203146 0.77 HSD17B10 (0.44) CA2HTTKDM4EMEN1MAPT
SCHEMBL19196140 0.77 GLRA3 (0.47) HTTKDM4EMEN1MAPTKMT2A
SCHEMBL19192061 0.71 HTT (0.47) LMNAHTTKDM4EMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11739223-B2 Surface primer compositions and methods of use ENVISTA (US) 2023-08-29 — — US disclosed
US-10696698-B2 Surface primer compositions and methods of use ORMCO CORPORATION 2020-06-30 — — US disclosed
US-20170217999-A1 SURFACE PRIMER COMPOSITIONS AND METHODS OF USE ORMCO CORPORATION 2017-08-03 — — US disclosed
US-20170217999-A1 SURFACE PRIMER COMPOSITIONS AND METHODS OF USE ORMCO CORPORATION 2017-08-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10696698-B2 Surface primer compositions and methods of use SP1, GPER1, GRIN1 CA2 2282/4885LMNA 2155/4885HTT 4681/4885
US-20170217999-A1 SURFACE PRIMER COMPOSITIONS AND METHODS OF USE SP1, GPER1, GRIN1 CA2 2282/4885LMNA 2155/4885HTT 4681/4885
US-11739223-B2 Surface primer compositions and methods of use SP1, GPER1, GRIN1 CA2 2282/4885LMNA 2155/4885HTT 4681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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