Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19197043 | 0.99 | TLR7 (1.00) | TLR8TLR7 | |
| SCHEMBL19196816 | 0.97 | TLR8 (1.00) | TLR8TLR7 | |
| SCHEMBL19181353 | 0.94 | TLR8 (1.00) | TLR8TLR7 | |
| SCHEMBL20968311 | 0.93 | TLR7 (1.00) | TLR8TLR7 | |
| SCHEMBL20968329 | 0.92 | TLR7 (1.00) | TLR8TLR7 | |
| SCHEMBL19196891 | 0.91 | TLR7 (0.87) | TLR8TLR7 | |
| SCHEMBL19196888 | 0.91 | TLR7 (1.00) | TLR8TLR7 | |
| SCHEMBL19196817 | 0.91 | TLR7 (0.87) | TLR8TLR7 | |
| SCHEMBL14758203 | 0.91 | TLR7 (1.00) | TLR8TLR7 | |
| SCHEMBL19196889 | 0.90 | TLR7 (1.00) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11279701-B2 | Immunomodulators and immunomodulator conjugates | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2022-03-22 | — | — | US | disclosed |
| US-20200325136-A1 | IMMUNOMODULATORS AND IMMUNOMODULATOR CONJUGATES | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2020-10-15 | — | — | US | disclosed |
| US-10730871-B2 | Immunomodulators and immunomodulator conjugates | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2020-08-04 | — | — | US | disclosed |
| US-20190127368-A1 | NLRP3 MODULATORS | IFM THERAPEUTICS INC (US) | 2019-05-02 | — | — | US | disclosed |
| US-20170217960-A1 | IMMUNOMODULATORS AND IMMUNOMODULATOR CONJUGATES | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2017-08-03 | — | — | US | disclosed |
| US-20170217960-A1 | IMMUNOMODULATORS AND IMMUNOMODULATOR CONJUGATES | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10730871-B2 | Immunomodulators and immunomodulator conjugates | CD40, CD47, FCGRT | TLR8 184/4885TLR7 124/4885 |
| US-20190127368-A1 | NLRP3 MODULATORS | NLRP3, TLR7, TLR8 | TLR8 3/4885TLR7 2/4885 |
| US-11279701-B2 | Immunomodulators and immunomodulator conjugates | IL2, CD47, FCGRT | TLR8 99/4885TLR7 44/4885 |
| US-20170217960-A1 | IMMUNOMODULATORS AND IMMUNOMODULATOR CONJUGATES | CD47, CD40, HLA-DRB1 | TLR8 150/4885TLR7 115/4885 |
| US-20200325136-A1 | IMMUNOMODULATORS AND IMMUNOMODULATOR CONJUGATES | IL2, CD47, FCGRT | TLR8 99/4885TLR7 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.