Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 5/20 | 0.39 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 2/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10009929 | 0.90 | HRH3 (0.43) | GPR52HDAC2HRH3FFAR1RXRA | |
| SCHEMBL14038099 | 0.85 | ESR1 (0.48) | GPR52HDAC2PTGS2 | |
| SCHEMBL18199532 | 0.85 | ESR1 (0.48) | GPR52HDAC2PTGS2 | |
| SCHEMBL19326441 | 0.82 | CYP1A2 (0.43) | GPR52HRH3FFAR1 | |
| SCHEMBL21901329 | 0.82 | CYP1A2 (0.43) | GPR52HRH3FFAR1 | |
| SCHEMBL23168311 | 0.82 | GPR52 (0.51) | GPR52HDAC2FFAR1TSHR | |
| SCHEMBL8838348 | 0.82 | GPR52 (0.51) | GPR52HDAC2FFAR1TSHR | |
| SCHEMBL14027701 | 0.81 | MAOB (0.50) | HRH3PTGS2 | |
| SCHEMBL10824095 | 0.81 | MAOB (0.50) | HRH3 | |
| SCHEMBL18540213 | 0.80 | GPR52 (0.43) | GPR52HDAC2HRH3FFAR1RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170218271-A1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME | DIC CORPORATION (JP) | 2017-08-03 | — | — | US | disclosed |